Characterization of Cycloartane-Type Sapogenol Derivatives for Prostate Cancer Chemoprevention
نویسندگان
چکیده
منابع مشابه
Chemoprevention of Prostate Cancer
Prostate cancer (PCa) is a very heterogeneous disease with a wide spectrum of clinical presentations and consequences. Indeed, if microscopic foci of adenocarcinoma can be found in the prostate of many men, only a minority will progress to clinically relevant, symptomatic, or potentially lethal disease. This explains the striking difference between the incidence of PCa and its mortality rate. I...
متن کاملDietary Botanicals for Chemoprevention of Prostate Cancer
Prostate cancer typically develops later in life. Hence, identi‐ fying the botanical compounds that can prevent or delay disease progression may have a positive effect on the quality of life and reduce the healthcare costs of the aging population.[1] Supporting the statement, it could be accepted that the burden of increasing morbidity and mortality due to prostate cancer imposes a need for new...
متن کاملNovel targets for prostate cancer chemoprevention.
Among many endocrine-related cancers, prostate cancer (PCa) is the most frequent male malignancy, and it is the second most common cause of cancer-related death in men in the United States. Therefore, this review focuses on summarizing the knowledge of molecular signaling pathways in PCa because, in order to better design new preventive strategies for the fight against PCa, documentation of the...
متن کاملChemoprevention of prostate cancer: myths and realities.
BACKGROUND Prostate cancer will affect 15% to 18% of men in North America and will result in death in 3%. Established curative and palliative treatments for prostate cancer are associated with significant morbidity and cost. For these reasons, prostate cancer is an ideal target for prevention. METHODS Using MEDLINE we performed a systematic review of clinical trials that have investigated pha...
متن کاملMechanisms of action of novel agents for prostate cancer chemoprevention.
Despite advances in the understanding of prostate cancer (PCa) growth and development, it is still the leading incidence of cases and the second leading cause of mortality due to cancer in men. The problem of early diagnosis compounded with the emergence of androgen independence during commonly used anti-androgen therapy of PCa, have been discouraging for optimal therapeutic response. Recently,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings
سال: 2017
ISSN: 2504-3900
DOI: 10.3390/proceedings1100985